Botox May Lose Effectiveness Over Time

 In Botox

Botox-194x300Perfect for frown lines, crow’s feet and forehead wrinkles, Botox has been a favored wrinkle treatment since its FDA-approval all the way back in 2002.

Botox has also been approved for a number of non-cosmetic uses including urinary incontinence (overactive bladder), eyelid spasms, migraine headaches, strabismus (crossed eyes) and more.

But those relying too heavily on Botox might actually be reducing its effectiveness over time.

A new review published by German researchers in the Journal of Neural Transmission discovered that one in every 200 users develops antibodies (similar to how people become resistant to antibiotics) which counteract the effects of Botox.

Patients who used Botox for 10 years or more, or required larger doses, like those using Botox to treat hyperhidrosis (excessive sweating), spasms or other medical conditions, were the most likely to develop antibodies.

Other researchers who published in the British Medical Journal’s online forum also wrote that regular treatments with Botox “can trigger an immune response… which might lead to non-responsiveness to treatment,” as the injections are unable to freeze facial muscles.

Unfortunately, researchers can’t yet explain the immune response that occurs in some patients – but some believe it may partially be related to injection technique.

Others feel the phenomena could be explained by further studying the different mechanics of Botox and how it works within cells.

Are you considering Botox?

Resistance to Botox is rare – so if you’re considering treatment, it’s best to schedule a personal consultation with a qualified cosmetic surgeon. Following an exam and a discussion of your cosmetic goals, your doctor will be able to determine if Botox is the best treatment available for you.

Source: Daily Mail

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